Beta
361056

Contribution in the quality assessment of Myrrh

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Chemistry of natural products

Abstract

Myrrh was used anciently in difficult cultures as in embalming fluids by Egyptians, in Chinese and other traditional medicine. However, research about activity of myrrh till now is not very convincing. Compendial description of myrrh wasn't helpful nor convenient in fully describing the composition as well as the attributes of the nature of myrrh, which put a burden on healthcare providers to appropriately prescribe it as it lacks the adequate validation tool in its healing properties or practices.
Methods used were descriptive parameters, such as color and particle size. Furthermore, we enforced chemical instrumental procedures, such as near infrared spectra, Thin layer chromatography and ultraviolet spectroscopy profiling. In conclusion, in vitro biological α-glucosidase activity of myrrh was assigned.
Impartially, NIR spectra of Myrrh were recorded and attempt to assign peaks of myrrh's chemical composition, this is the first study to use this approach for myrrh. Particle size and color-PLS models with low RMSEC and RMSECV was useful to estimate alpha-glucosidase inhibitory activity with acceptable accuracy.
In the absence of evidence based therapeutic indication for myrrh chemistry we must accurately study the composition of myrrh and agree upon species.

DOI

10.21608/rpbs.2024.291175.1297

Keywords

myrrh quality, near infrared, RGB, alpha-glucosidase inhibition, PLS

Authors

First Name

hoda

Last Name

fathy

MiddleName

-

Affiliation

1 elkhartoum square

Email

hodasherif@hotmail.com

City

alexandria

Orcid

-

First Name

Reham

Last Name

Ibrahim

MiddleName

-

Affiliation

Faculty of pharmacy, pharmacognosy department

Email

rehamsaid84@yahoo.com

City

Alexandria

Orcid

-

First Name

yomna

Last Name

khaled

MiddleName

-

Affiliation

faculty of pharmacy and drug manufacturing, pharos university

Email

yomna_khaled@hotmail.com

City

-

Orcid

-

First Name

mohamed

Last Name

aboushoer

MiddleName

-

Affiliation

faculty of pharmacy, alexandria university

Email

aboushoerm@yahoo.com

City

-

Orcid

-

Volume

8

Article Issue

2

Related Issue

47568

Issue Date

2024-05-01

Receive Date

2024-05-20

Publish Date

2024-05-01

Page Start

46

Page End

64

Print ISSN

2536-9857

Online ISSN

2535-2091

Link

https://rpbs.journals.ekb.eg/article_361056.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=361056

Order

361,056

Type

Original Article

Type Code

532

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

Contribution in the quality assessment of Myrrh

Details

Type

Article

Created At

23 Dec 2024