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292705

Natural product biosynthesis in bacteria associated with marine organisms

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Last updated: 03 Jan 2025

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Abstract

Because antibiotics are becoming less effective and there is an increase in the number of cases of cancer, it is critical that researchers continue their search for novel natural antimicrobials and anti-cancer medicines. Screening marine organisms for the purpose of developing new medications is still in its infant stages especially from nudibranchs. Many Polyketides, non-ribosomal peptides, terpenes, and post-ribosomal peptides are synthesized by marine organisms' symbiotic bacteria. In this review, we summarized the sum of the previous works done on bacteria associated with marine organisms for identifying bioactive metabolites. We discussed whether the host is responsible for the production of these metabolites or its symbiotic bacteria. Also, factors that may affect the abundance of symbiotic bacteria and bioactive compounds such as different habitats and environmental circumstances like food and location have been shown and discussed. We also discussed why nudibranchs deserve more studies for mining secondary metabolites in their symbiotic bacteria.

DOI

10.21608/rpbs.2023.196300.1212

Keywords

nudibranchs, symbiotic bacteria, Natural product, secondary metabolites

Authors

First Name

Esraa

Last Name

Elsaeed

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt

Email

esraaelsaeed86@gmail.com

City

-

Orcid

0000-0003-3453-7490

First Name

shymaa

Last Name

Enany

MiddleName

mohamed

Affiliation

department of microbiology and immunology, faculty of pharmacy, Ismailia, Egypt

Email

shymaa21@yahoo.com

City

ismailia

Orcid

0000-0002-7827-6504

First Name

Samar

Last Name

Solyman

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt

Email

samar.solyman@pharm.suez.edu.eg

City

-

Orcid

0000-0002-8450-5940

First Name

Mohamed

Last Name

Shohayeba

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt

Email

shohayeb@hotmail.com

City

-

Orcid

-

First Name

Amro

Last Name

Hanora

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt

Email

ahanora@yahoo.com

City

-

Orcid

0000-0003-4937-7741

Volume

7

Article Issue

2

Related Issue

38938

Issue Date

2023-01-01

Receive Date

2023-02-25

Publish Date

2023-01-01

Page Start

67

Page End

79

Print ISSN

2536-9857

Online ISSN

2535-2091

Article File

RPBS_Volume 7_Issue 2_Pages 67-79.pdf

PDF . 514.6kB

Link

https://rpbs.journals.ekb.eg/article_292705.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=292705

Order

292,705

Type

Mini-reviews

Type Code

534

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

Natural product biosynthesis in bacteria associated with marine organisms

Details

Type

Article

Created At

23 Dec 2024