Amaranthaceae is a family of flowering plants. It is often containing isoflavonoids. In phytochemical research, various methylene dioxyflavonols, saponins, triterpenoids, ecdysteroids, and specific carbohydrates have been found in the roots. There are around 165 genera and 2,040 species in it. The flowering plant species Cornulaca monacantha is now a member of the Amaranthaceae family and belongs to the genus Cornulaca (formerly Chenopodiaceae). It is a type of desert plant that can be found throughout the Middle East and the Sahara; the southern limit of its distribution is thought to mark the edge of the desert. C. monacantha is an annual herb with thorny leaves that are highly ramified from the base and turn yellow when dried. It has been recognized as an important medicinal plant with different use. The plant is used to cure liver issues including jaundice. It is also regarded as a superior camel pasture, particularly for its impact on milk production. Few studies have been conducted on the chemical composition of C. monacantha, hence little is known about its phytochemical content. Thirteen triterpenoid saponins, six flavonoids, including derivatives of quercetin and luteolin, thirteen triterpenoid saponins, four gallotannin analogues, including monacanthin A and monacanthin B. In Arabic it is known as had and djouri, and the Tuareg people call it tahara. It was first described in 1813 by the French botanist Alire Raffeneau Delile.