Anthelmintics drugs are used to treat infectious diseases in the intestinal tract of animals caused by parasitic worms. These drugs are important in the livestock industry for controlling coccidiosis, a parasitic disease that can have significant economic impacts. The excessive use of these agents in the poultry and livestock industries, and their continuous use has led to the development of resistance in the parasites they target. veterinary drug residues in food are a significant concern, and their detection, prevention, and management are crucial to ensure food safety and protect consumer health. Therefore, for public health concern, regulatory authorities have established guidelines to control the limit of veterinary residues in animals and their different food products. Sample preparations and analytical techniques are crucial for detecting veterinary medication residues in foods generated from animals, maintaining food safety. Various extraction methods such as LLE, SPE and MSPD are used for the determination of veterinary drug residues, and analytical techniques like spectroscopic and chromatographic methods are employed for this purpose.