This work was carried out to examine the possibility of Eichhornia affecting cellular damage by using different or several measurements, such as mitotic activity, meotic activity, and histology of the liver and kidney. The obtained results clearly and precisely showed that Eichhornia sap was proven to enhance cellular activity and did not affect the liver as well as kidney cells, giving strong evidence that Eichhornia sap is useful for human usage. Cyclophosphamide (the generic name for Endoxan, Cytoxan) is an alkylating agent. It is used to treat a variety of different cancers (breast cancer, ovarian cancer, and certain types of leukemia). Its side effects are carcinogenic, Teratogenic, and Infertility. However, cyclophosphamide was used as a positive control as it was mainly used in genetic toxicology experiments. The possibility of use of water hyacinth for used. The appearance of secondary metabolite components for medicinal and curative purposes such as anticancer, antimicrobials, antioxidants, anti-dandruff, and antiproliferative actions and provides a possibility source for animal feed because of the high rates of carbohydrates, raw proteins, and raw fibers.