The powdery mildew of mango caused by Oidium mangiferae has become a serious and widespread problem in many parts of Egypt. A field experiment was conducted for four seasons 2019-2022 to investigate the efficacy of four fungicides, COBOX 50% WP (Copper Oxchloride), TOPAS 10% EC (Penconazole), PUNCH 40%EC (flusilazole and Carbendazim) and KEMAZED 50%WP (Carbendazim) along with control (water spray) against mango powdery mildew on the most popular cv. Taimour. Each fungicide was sprayed in 15-d-intervals with di-potassium phosphate, mono-potassium phosphate, and calcium phosphate alone in one season in 2019 at two governorates (Aldaqahlia and Domietta). Under ALmansoura condition, the best treatment was TOPAS, which recorded 15.75 and 26.25% disease severity compared with control which recorded 67.5 and 74.25% disease severity on the leaves and blooms, respectively. The integrated control program combined the fertilizers with fungicides in three successive seasons 2020,2021 and 2022. This program was decreasing the disease and also was decreasing the number of sprays fungicides so this study gained eco-friendly methods to control a serious disease and cost saving and the most important is decreeing the residual effect of pesticides in fruits.