This paper indicates the importance of nanotechnology in many fields, especially in the field of architecture and finishes. Then it refers to the importance of thermal insulation made using nanotechnology used as an alternative to traditional insulation materials, which achieve thermal comfort within administrative buildings in coastal areas, which reduces the consumption of electrical energy needed by the building to reach the appropriate degree of cooling, as all studies indicate that walls and ceilings allow entry of 60-70 % of the external heat surrounding the building and the remaining percentage penetrates the building through windows and doors. The research paper also includes a case study of an administrative building in one of the gas fields in Port Said using a simulation tool, which is the Design Builder program, which know through it the extent of electrical energy consumption from heating, ventilation and air-conditioning (HVAC) within the building. By introducing two thermal insulation materials that were manufactured using nanotechnology the 1st for insulation the walls are nano-ceramic insulation coating, and the second for ceilings is vacuum insulation panels as an alternative to traditional materials. The study also showed the use of each isolation material separately and the extent of its impact. Whether roof insulation only or wall insulation only and insert the two materials Together to see the comprehensive development and the actual impact on consumption. Keywords: nanotechnology - thermal comfort - energy saving - thermal insulation materials.