One hundred individuals as 12 blood samples for each breed of Fayumi and Dandarawi, 100 for all parameters and 12 for genetic parameters with the GH, GHR, IGFBP-II, HSP70 and HSP90 gene were assayed. When compared to the Fayoumi chicken breed, Dandarawi had higher in body weights. Furthermore, the averages of total Cytosine and Guanine (C+G) in the Dandarawi chicken breed were 148.5 nucleotides. These facts would suggest that the Dandarawi allow it to adapt to hot climate environments with the genes had it and is thus selected to increase production under hot environments. The GH1, GH2, GHR, IGFBPII, HSP70, and HSP90 genes had greatly informative markers that have values of PIC >0.50 with two chicken breeds. The T and C were identified as highly variable sites in the GH1 gene at positions 275 and 338 for non-coding regions, respectively. Also, the convert of T to G were found in positions of 26, 95, 130, 167 and 171 for non-coding regions, respectively in GH2 gene. Moreover, the highly variations identified T to C were in positions of non-coding regions, respectively in GHR and IGFBPII gene. Finally, the variations identified C to G and A to C were in positions for coding regions, respectively in HSP90 gene. The highly polymorphic regions of 18 positions were detected  for GH2 in non-coding regions with two chicken breeds. The polymorphism with the lowest value was one with HSP70 in the coding area and two chicken breeds. Therefore, the results point to that the genes of HSP90, 70 in the Dandarawi breed might function well under HS than the Fayoumi chicken breed. It was discovered that a single nucleotide polymorphism in HSP70 gene resulted from the amino acid cysteine being used in state of arginine due to the replacement of the T nucleotide with C. The differences between the breeds indicated the variance, which redirect the opportunity of continuing the choice database.