The present study carried out to present the legal frame of the international and national nuclear and radiological programs. Nuclear and radiological programs and control are the backbone of the measure of the progress of countries at present. Almost all developed countries have integrated nuclear and radiological programs, and even developing countries seek to possess that technology to catch up with progress. One will talk here about the activities of Egyptian nuclear and radiological program. Nuclear and radiological programs generally consist of six activities. These six activities can be divided into three groups, the first set of activities represents the nuclear part of the programs, namely reactors of both types and their respective nuclear fuel circuits. The second set of activities includes all radiological activities such as radiological facilities and radioactive waste management facilities, while the third group includes the safe transport of radioactive materials whether nuclear or non-nuclear. The Egyptian programs consists only of 5 activates, since the delay in the implementation of nuclear plants and their fuel department, due to political, strategic and international technical constraints. Egypt's radiation nuclear program consists of five activities exclusively: research reactors and its complementary fuel department; radiological facilities, namely accelerators, gamma irradiation units; facilities using radioactive isotopes and sealed radioactive sources such as hospitals and laboratories, laboratories at universities and research centers, industrial use of radioactive materials; radioactive waste management facilities; and safe transport of radioactive materials.