Cognition refers to all the processes by which the sensory input is transformed, reduced, elaborated, stored, recovered, and used. Polyphenols are powerful antioxidant and regular intake of polyphenol-rich food caused a positive impact on cognitive outcomes. This study investigates the effect of some natural antioxidant (quercetin, caffeic acid, P-coumaric acid and ferulic acid) supplementation in cognition of 27children  aged (7– 13) years in the primary school (Al-Azhar Primary Institutes) with learning disabilities measure which were diagnosed by the psychologist and their teachers. Some forms and tests were used before and after antioxidant supplementation including Intelligence tests(Stanford Penny), learning disabilities measure (cognition), Personal data, Anthropometric measurements, and nutritional assessment. The application of food intervention was carried out by providing one category of meals daily, meal 1 contains (vanilla biscuit with yellow corn meal + fruit cake with cocoa jelly), meal 2 contains (chocolate cupcake with yellow corn meal +fruit cake with red beet roots jelly) and meal 3 contains (chocolate peanut butter biscuits+ vegetables salad) for 3 months frequency. Meals are rich in polyphenols as (quercetin, caffeic acid, P-coumaric acid and ferulic acid) caused highly significant increase (p≤ 0.01) in the mean value of cognition (23.88±2097) as compared before test (15.11± 2.43). It was also observed an improvements in some behavioral and nutritional problems. It could be concluded that, dietary intervention rich in polyphenols may improve cognition in children with learning disabilities.