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298595

Review: Correlation between Type 1 Diabetes Mellitus and Gut Microbiome

Article

Last updated: 03 Jan 2025

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Tags

Nutritional quality of novel foods

Abstract

Diabetes mellitus (DM) is one of the most common metabolic disorders all over the world. Type 1 diabetes (T1D) is a subtype of DM that is characterized by autoimmunity and B-cell destruction. T1D is considered a disease of multifactorial origin with genetic susceptibility and environmental factors. The environmental (triggering) factors are numerous and including gut microbiome (GM). GM is a humorous dynamic population of microbes that harbor the intestine and have a marked effect on our metabolic diseases and homeostasis. Many studies found that dysbiosis and compositional changes in GM play important roles in T1D development. The objective of this study was to determine the correlation between T1D and GM to establish the best strategies for microbiome alteration to assist in the prevention of T1D occurrence and for better glycaemic control in the near future. The search studies address the question of the relationship between T1D and GM. All available data provided by PubMed/MEDLINE, Google Scholar, Springer Link, EM base Medline, and Cochrane Library were reviewed to fulfill the required objectives. Conclusion: Diet can alter the onset and course of autoimmune disorders including T1D by modifying the gut microbiome.

DOI

10.21608/bnni.2023.298595

Keywords

Diabetes mellitus, T1D, GUT microbiome

Authors

First Name

Nebal

Last Name

Abo-Elaala

MiddleName

A

Affiliation

Department of Clinical Nutrition, National Nutrition Institute NNI, Cairo, Egypt.

Email

-

City

Cairo

Orcid

-

First Name

Ahmed

Last Name

Mohamed

MiddleName

G

Affiliation

Ministry of Health and Population, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Mohamed

Last Name

Mayez

MiddleName

M

Affiliation

Ministry of Health and Population, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Karema

Last Name

Ahmed

MiddleName

A

Affiliation

Ministry of Health and Population, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Walid

Last Name

Abd-Almajid

MiddleName

M

Affiliation

Ministry of Health and Population, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Mohammed

Last Name

Abd El-Megied

MiddleName

A

Affiliation

Department of Pediatrics, Faculty of Medicine, Cairo University, Egypt

Email

-

City

Cairo

Orcid

-

Volume

61

Article Issue

1

Related Issue

39752

Issue Date

2023-06-01

Receive Date

2023-05-10

Publish Date

2023-06-01

Page Start

138

Page End

167

Print ISSN

1110-0974

Online ISSN

2537-0987

Article File

BNNI_Volume 61_Issue 1_Pages 138-167.pdf

PDF . 558.4kB

Link

https://bnni.journals.ekb.eg/article_298595.html

Detail API

https://bnni.journals.ekb.eg/service?article_code=298595

Order

298,595

Type

Original Article

Type Code

442

Publication Type

Journal

Publication Title

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt

Publication Link

https://bnni.journals.ekb.eg/

MainTitle

Review: Correlation between Type 1 Diabetes Mellitus and Gut Microbiome

Details

Type

Article

Created At

23 Dec 2024