Background: Energy drinks (EDs) have become a mainstay for many people looking for a quick energy boost thanks to their enormous rise in popularity in recent years. However, several studies have brought attention to the possible negative health consequences linked to the intake of these drinks. Objective:  This study aimed to look into the impact of EDs on liver biochemical, liver histology, and glucose levels as well. Materials and methods: Three groups of rats were placed: control group, red bull group, and power horse group, each receiving a regular diet and daily red bull energy drink. liver, kidney, glucose, and insulin were evaluated. Further, histological examination was evaluated. Results: ALT and AST blood levels were significantly higher in the energy drink groups compared to the control group. There were no significant differences in AST and ALT levels between the energy drink groups. Serum creatinine levels were also significantly higher in the energy drink groups compared to the control group, with no significant difference between the energy drink groups. Random blood sugar levels were significantly higher in the energy drink groups compared to the control group, with no significant differences between the energy drink groups. Insulin levels were significantly higher in the power horse group compared to both the red bull and control groups, but there was no significant change between the control and red bull groups. Additionally, liver damage was confirmed by biopsy in patients who had ingested EDs. Conclusion: The use of EDs like red bull and power horse has been shown to have serious adverse effects on the liver. Consequently, it is important to be aware of the potential health risks associated with consuming these energy drinks.