350511

Patterns of biopsy-proved glomerular injury in Egyptian geriatric patients.

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Last updated: 03 Jan 2025

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Abstract

Background: Chronic kidney disease (CKD) is considered a large burden in the elderly population. Many risk factors have been identified, however the pattern of involvement in this population remains unclear. Objectives: To detect the pattern of glomerular injury in the Egyptian geriatric population. Methods: We performed a single-centre, retrospective descriptive study on biopsy-proven renal diseases at Ain Shams University Pathology Unit; we included all biopsies with proven glomerular disease in geriatric patients aged ≥ 60 years (from 2018 to April 2023) to detect the pattern of glomerular injury in these patients throughout the last five years Results: Ninety-six renal biopsies with proved glomerular injury were included. In our study the mean age was 66.938±5.068, also 27.08% of our population were diabetic while 56.25% were hypertensive. Mean values for serum creatinine and protein/creatinine ratio on presentation are 4.240±2.20 and 4.257±1.97 respectively. In our study the majority of biopsies showed Focal segmental Glomerulosclerosis (30.21%), it was followed by Membranous Glomerulonephritis (12.5%), Diabetic Glomerulosclerosis, Diffuse Proliferative Glomerulonephritis and Diffuse Glomerulosclerosis came next (11.46,11.46 and 10.42 % respectively) Conclusion: Focal segmental glomerulosclerosis seemed to be the most prevalent type of glomerulonephritis in elderly Egyptian patients although these results need to verify on a larger scale of patients.

DOI

10.21608/ejgg.2024.350511

Keywords

Glomerulonephritis, Elderly, geriatric

Authors

First Name

Norhan

Last Name

Magdi Madbouli

MiddleName

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Affiliation

Department of Internal Medicine and Nephrology, Ain Shams University, Cairo, Egypt

Email

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City

Cairo

Orcid

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First Name

Menna

Last Name

Abdelghany Aly

MiddleName

-

Affiliation

Department of Geriatrics, Ain Shams University, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Manal

Last Name

Ibrahim Salman

MiddleName

-

Affiliation

Department of Pathology, Ain Shams University, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Ahmed

Last Name

El Borolosy

MiddleName

-

Affiliation

Department of Internal Medicine, Modern University for Technology and Information

Email

-

City

Cairo

Orcid

-

First Name

Sara

Last Name

Farid Samaan

MiddleName

-

Affiliation

Department of Internal Medicine and Rheumatology, Ain Shams University, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

Volume

11

Article Issue

1

Related Issue

47161

Issue Date

2024-03-01

Receive Date

2024-04-16

Publish Date

2024-03-01

Page Start

1

Page End

11

Print ISSN

2356-8712

Online ISSN

2536-9792

Link

https://ejgg.journals.ekb.eg/article_350511.html

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https://ejgg.journals.ekb.eg/service?article_code=350511

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Original Article

Type Code

365

Publication Type

Journal

Publication Title

The Egyptian Journal of Geriatrics and Gerontology

Publication Link

https://ejgg.journals.ekb.eg/

MainTitle

Patterns of biopsy-proved glomerular injury in Egyptian geriatric patients.

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Article

Created At

23 Dec 2024