Background: Nearly 7.7 million children under the age of five die annually on a global scale; approximately 3.1 million newborns die during the neonatal period, and almost all of these fatalities (99%) occur in developing nations. This study aims to evaluate the knowledge, attitudes, and behaviours of mothers in the Fayoum Governorate. Methods: Across -sectional study will include 400 mothers inFayoumgovernorate.Newborncareknowledgeandattitudewillbeobserved among 400 mothers. Structured interview questionnaire will be used to collect the data. Results: About half of mothers(48.0%)reportedthattheyvisitedtheprenatalclinic.Majorityofthem170/180(94.4%)received message on breast feeding followed by umbilical cord care (55.6%),received anti-tetanus toxoid during this or previous pregnancy Most mothers reported that their neonates (68.0%)had delivered by CS. As regards the attitude of mothers about dangerous sign of the neonate, most of mothers specified appositive attitude with a percentageover50%inalltopics.Conclusion: The prevention of neonatal mortality is reliant on maternal knowledge and practise regarding new born care. Some sociodemographic variables may be associated with the knowledge and practises of mothers. Educating the mothers as well as their family members is crucial.Keywords:Neonatalcare,Postnatalmothers,Knowledge-Attitude-Practice(KAP).