Introduction: COVID-19 began a worldwide public health emergency with high mortality rate when it started to spread 2019 in China. It caused millions of deaths within less than two years.
Aim of the study: Evaluation of clinical, laboratory and radiological parameters of COVID-19 patients as well as therapeutic management; and assessment of their impact as outcome predictors.
Subjects and Methods: We investigated 210 patients admitted to the critical care department at Fayoum university hospitals with PCR-confirmed COVID-19, from April 2020 to September 2021. We separated our patients into two groups: survival group (group I) and mortality group (group II ).
Results: Our study revealed that among our ICU-admitted patients with COVID19; those with higher mortality were older, more overweight ,had higher CRP (60.0 ± 54. in group I vs. 78.9 ± 67.2 in group II, P<0.05) , higher D-dimer level (1.5±1.4 in Group I vs. 2.4±1.9 in Group II, P<0.01), higher LDH , higher IL6 (139.9±640.3 in Group I vs. 560.5 ± 1163.7 in Group II, P<0.05) and less serum albumin level upon ICU admission . Also, mortality was less in patients with lower CORAD score in CT chest, less affected lung lobes , less APACHE II score.
Conclusions: Our study showed that age and weight of COVID-19 patients together with many laboratory and radiological parameters could be good predictors of mortality upon ICU admission