Introduction: One of the most important fat-soluble vitamins is vitamin D. Hypovitaminosis D has been linked to dysfunction in sexual activity in both healthy females and males with erectile dysfunction. Detecting the impact of vitamin D on female sexual activity via the estrogen and testosterone hormones is an intriguing research topic.
Aim of the study: The target of this research is to examine the role of vitamin D on female sexual dysfunction and in what way.
Subjects and methods: This meta-analysis follows the PRISMA flow diagram. This research aims to detect the impact of vitamin D on female sexual function by measuring vitamin D, testosterone, and estrogen serum levels in cases with FSD compared with normal females.
Results: After the search and screening, one study was eligible for inclusion in our meta-analysis. Results of the meta-analysis show that the quantity of serum vitamin D3 was decreased in females with FSD compared with controls, and the domain scores were also connected with the amounts of vitamin D3. There was a statistically significant negative relationship between the BDI and the whole FSFI scale. There is no statistically significant relationship between hormone levels and the Female Sexual Function Index.
Conclusion: Our findings show that there is an association between vitamin D insufficiency and female sexual dysfunction. FSD was also associated with depression symptoms.