The present study was conducted on Salvia officinalis L. plants throughout two successive seasons in 2020/2021 and 2021/2022 at a private farm in Fayoum Governorate, Egypt. The experiments aimed to find out the individual and the combined effects of nitrogen at three concentrations in the form of ammonium nitrate (33.5%N) at 0, 2 and 4 g/plant under two types of soils (clay and sandy soils) on vegetative growth, chemical composition and essential oil components of salvia officinalis. The results emphasized that using nitrogen fertilizer under two types of soils had significant response on all parameters in this study. Likewise, these treatments supported vegetative growth parameters, promoted chemical composition as well as, increased oil percentage and chemical constituents of essential oil, especially with using clay soil and high level of nitrogen (4 g/plant), the interaction between levels of nitrogen fertilizer improved all the studied parameters under clay soil.