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388585

Diagnostic Accuracy of MRI for Cervical Malignancy with Histopathologic Correlation

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Last updated: 23 Dec 2024

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Abstract

Background and Aim: The determination of lymph node metastases, parametrial invasion, and pelvic side wall invasion—all known to be significant prognostic factors—as well as the precise measurement of tumor size present the greatest challenges in cervical cancer. The only gynaecological cancer that is currently primarily staged clinically, according to the FIGO classification, is cervical cancer. The aim of this work is to evaluate the role of MRI in the accurate staging of cancer cervix compared to clinical FIGO staging.  
Methods: This prospective study included 21 patients (19 with primarily untreated pathologically proven cervical cancer who underwent pretreatment MRI and 2 post chemo-radiotherapy cases who underwent post-treatment MRI).  
Results: This study found that 100% sensitivity and 100% specificity in detecting parametrial invasion contrasts with clinical staging's 20% sensitivity. Vaginal invasion may be detected with 100% sensitivity in both stage IIA and IIIA using MRI, which is very sensitive. A hyperintense vaginal thickening (tumor) or the mass itself next to the vaginal wall are the two most clear indicators of vaginal involvement on high-resolution T2-weighted sequences. These sequences also indicate the segmental discontinuity of the typical hypointense signal of the vaginal wall. Stage IIa is represented by vaginal invasion, and stage IIIa is represented when this invasion reaches the lower vaginal third. 
Conclusions: Research has demonstrated that MRI is superior to clinical examinations. When used as the first staging technique, it enables accurate evaluation of the tumor's volume and extension, which improves field planning for external pelvic radiation and brachytherapy.

DOI

10.21608/egyfs.2024.388585

Keywords

Key words: MRI, Cervical Cancer, histopathology. 

Authors

First Name

Ahmed

Last Name

Mamdouh

MiddleName

Mohamed

Affiliation

Assistant Professor of Obstetrics & Gynaecology, Ain Shams University

Email

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City

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Orcid

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First Name

Amr

Last Name

Saad

MiddleName

-

Affiliation

Lecturer of Obstetrics & Gynaecology, Ain Shams University

Email

amrsaadobygyn@gmail.com

City

-

Orcid

-

First Name

Hassan

Last Name

Morsi

MiddleName

-

Affiliation

Assistant Professor of Obstetrics & Gynaecology, Ain Shams University, Obstetrics & Gynaecology Department, Abbassia Square, Cairo

Email

hassanmorsi@hotmail.com

City

-

Orcid

0000-0001-8008-9604

Volume

28

Article Issue

5

Related Issue

51208

Issue Date

2024-09-01

Receive Date

2024-10-22

Publish Date

2024-09-01

Page Start

3

Page End

9

Print ISSN

1110-6352

Online ISSN

2536-9768

Link

https://egyfs.journals.ekb.eg/article_388585.html

Detail API

https://egyfs.journals.ekb.eg/service?article_code=388585

Order

388,585

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

Diagnostic Accuracy of MRI for Cervical Malignancy with Histopathologic Correlation

Details

Type

Article

Created At

23 Dec 2024