363881

The role of corticosteroids in prevention of neonatal respiratory morbidity in term elective cesarean section: A prospective: observation study

Article

Last updated: 03 Jan 2025

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Abstract

Background : Caesarean sections continue to increase day by day in both developed and developing countries, which is associated with increased respiratory distress syndrome (RDS), the key reason for early neonatal morbidity and mortality.   
Objective: To assess the effect of routine prophylactic corticosteroids before elective caesarean section after 37 weeks of gestational age, on neonatal respiratory morbidity. Methods: A prospective observational study was conducted on all pregnant women undergoing elective caesarean sections between 37-42 weeks at Ain Shams University Maternity Hospital. Over an 8- month period (from November 2020 to June 2021), 1105 cases were divided into the exposed group (A), (N = 877) who received prophylactic dexamethasone, and 228 cases in the non-exposed group (B) who did not receive dexamethasone. Outcome measures were the incidence of transient tachypnea of the newborn, and NICU admissions due to respiratory morbidity. Data were analyzed using SPSS 22.  
Results: Overall, there was no statistically significant difference in the incidence of TTN or RDS. No cases of TTN were found in exposed subgroup, versus 1 (0.4%) in non-exposed group (p= 0.745). The respiratory distress (RDS) in the exposed subgroup was 4 cases (16.7%) versus 18 (7.9%) in
non-exposed group (p = 0.148). While the admission to the neonatal intensive care unit (NICU) due to respiratory morbidity after an elective caesarean section was 4 cases (16.7%) in the exposed subgroup versus 19 cases (8.3%) in the non-exposed group (p = 0.178).  
Conclusion: Routine administration of prophylactic antenatal corticosteroids before elective caesarean sections at term does not reduce the risk of admission to the NICU compared to non- administration.   

DOI

10.21608/egyfs.2024.363881

Keywords

Key Words: elective cesarean delivery, antenatal corticosteroid, respiratory morbidity. 

Authors

First Name

Mohamed

Last Name

Salama

MiddleName

H.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Faten

Last Name

Elposty

MiddleName

E.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Zeinhom

MiddleName

M.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Marwa

Last Name

Elgendi

MiddleName

A.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Ashraf

Last Name

Nabhan

MiddleName

F.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Noha

Last Name

Sakna

MiddleName

Abd El-Sattar

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University

Email

noha2877@yahoo.com

City

-

Orcid

0000-0001-6354-3190

Volume

28

Article Issue

3

Related Issue

48865

Issue Date

2024-05-01

Receive Date

2024-07-05

Publish Date

2024-05-01

Page Start

100

Page End

111

Print ISSN

1110-6352

Online ISSN

2536-9768

Link

https://egyfs.journals.ekb.eg/article_363881.html

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https://egyfs.journals.ekb.eg/service?article_code=363881

Order

363,881

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

The role of corticosteroids in prevention of neonatal respiratory morbidity in term elective cesarean section: A prospective: observation study

Details

Type

Article

Created At

23 Dec 2024