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345928

Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages

Article

Last updated: 23 Dec 2024

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Abstract

Background: Molar pregnancy is a rare complication of pregnancy characterized by the abnormal growth of trophoblasts, the cells that normally develop into the placenta. Routine histopathologic examination of uterine products is beneficial in protecting obstetrician and gynecologist from medico legal recrimination, but it is unclear whether this practice is medically justified.  
Objective: The aim of this study is to evaluate Prevalence of molar pregnancy in histopathological examination of products of conception following first trimester miscarriages.
Patients and Methods: This was a cross sectional study conducted on cases with products of conception in the first trimester miscarriages up to 12 weeks gestation. Entire cases were subjected to full history taking, clinical examination after that the samples were collected via manual vacuum aspiration for histopathological analysis.
Results: The prevalence of molar pregnancy among the studied cases was 7%. About 93% of the studied cases were normal. Most of the studied histological specimens were products of conception which accounts for 85% of cases. The incidence of complete vesicular mole, degenerated Products of conception, Hyper secretory Endometrium, Infected Products of conception, Necrotic Products of conception and Partial Hydatidiform moles were 4.2, 1.4, 2.8, 1.4, 1.4 and 2.8 respectively.
Conclusion: Histopathological examination seemed to be a promising tool in the context of assessment of products of conception in which the prevalence of molar pregnancy was 7%. In addition, incidence of molar pregnancy has no significant correlations with all clinical features as well as with blood groups.

DOI

10.21608/egyfs.2024.345928

Keywords

Keywords: Molar pregnancy, Histopathological examination, Products of conception. 

Authors

First Name

Mohamed

Last Name

Ezzat Eldesouki

MiddleName

Abdelmawla

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt

Email

doc.abdelmawla@gmail.com

City

-

Orcid

-

First Name

Osama

Last Name

Warda

MiddleName

Mahmoud

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt

Email

-

City

-

Orcid

-

First Name

Hanan

Last Name

Abdelhafez

MiddleName

Nabil

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt

Email

-

City

-

Orcid

-

First Name

Mahmoud

Last Name

Abdelrazek

MiddleName

Mohamed

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt

Email

-

City

-

Orcid

-

Volume

28

Article Issue

1

Related Issue

46373

Issue Date

2024-01-01

Receive Date

2024-03-15

Publish Date

2024-01-01

Page Start

39

Page End

50

Print ISSN

1110-6352

Online ISSN

2536-9768

Link

https://egyfs.journals.ekb.eg/article_345928.html

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https://egyfs.journals.ekb.eg/service?article_code=345928

Order

6

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

Prevalence of Molar Pregnancy in Histopathological Examination of Products of Conception Following First Trimester Miscarriages

Details

Type

Article

Created At

23 Dec 2024