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343710

Evaluation of the analgesic effect of Intraperitoneal instillation of lidocaine with and without meperidine versus non-steroidal anti-inflammatory drugs during and after gynecolog

Article

Last updated: 23 Dec 2024

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Abstract

Background: Drugs are used in a wide range to control pain as they are easy to apply by any route, fast, and effective. Also, they do not need special skills or techniques. But it may be dangerous if overdoses are given, leading to addiction or withdrawal symptoms, especially if used alone without sedation or muscle relaxant. 
Methods: In this study, two hundred cases were classified into four groups of patients undergoing minor laparoscopic procedures as diagnostic, ovarian drilling, adhesiolysis, ovarian cystectomy, ectopic pregnancy, endometriosis ablation, etc. Every group included 50 patients. Group I received intraperitoneal lidocaine. Group II received intraperitoneal lidocaine with meperidine. Group III received intramuscular NSAID drugs (diclofenac sodium) 75 mg. Group IV received intraperitoneal saline. Postoperative pain was assessed using a numeric pain rating scale. A highly significant difference between Group II and Group I or III was seen when the pain score across the four groups was examined at 0, 2, and 6 hours postoperatively. Comparing Group IV to the other groups, it is highly significant (high score). When the pain scores from the four groups were assessed at 12 hours postoperatively, groups I and II revealed a significant difference compared to group III. Comparing Group IV to the other groups reveals it is highly significant. So, We concluded that the "intraperitoneal lidocaine with or without meperidine" procedure was simple, risk-free, and without side effects. In contrast to non-steroidal anti-inflammatory drugs, intraperitoneally administered lidocaine, both with and without meperidine, significantly reduces postoperative discomfort after minor gynecologic laparoscopic surgery.

DOI

10.21608/egyfs.2024.343710

Authors

First Name

Ahmed

Last Name

Radwan

MiddleName

M.

Affiliation

Assistant Professor of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University

Email

ahmedradwan0072030@gmail.com

City

-

Orcid

-

First Name

Ehab

Last Name

Girbash

MiddleName

F.

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Taema

MiddleName

I

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University

Email

mohamed.taema@yahoo.com

City

-

Orcid

-

Volume

28

Article Issue

1

Related Issue

46373

Issue Date

2024-01-01

Receive Date

2024-02-29

Publish Date

2024-01-01

Page Start

3

Page End

9

Print ISSN

1110-6352

Online ISSN

2536-9768

Link

https://egyfs.journals.ekb.eg/article_343710.html

Detail API

https://egyfs.journals.ekb.eg/service?article_code=343710

Order

2

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

Evaluation of the analgesic effect of Intraperitoneal instillation of lidocaine with and without meperidine versus non-steroidal anti-inflammatory drugs during and after gynecological laparoscopic procedures

Details

Type

Article

Created At

23 Dec 2024