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286056

Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage

Article

Last updated: 23 Dec 2024

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Abstract

Background: Prophylactic antibiotics have been tradi- tionally used to prevent postoperative infection after sur- gical intervention for the first-trimester miscarriage. This work aims to study the role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage.
Methods: This study was conducted on 138 women who underwent surgical management of first-trimester mis- carriage. They were equally divided into two groups; the women in the study group were given a single dose of oral doxycycline (200 mg) and metronidazole (500 mg) 2 hours before the surgical procedure. The other group was given a placebo. Both groups were followed up for assessment of postoperative infection within two weeks.  
Results: According to the original strict criteria, the preva- lence of pelvic infection was found in 8.7% in the antibiotic group (6 out of 69) and 13% in the placebo group (9 out of 69), P=0.412. On follow-up, there was no significant differ- ence between the studied groups concerning postoperative complications.     
Conclusion: Prophylactic antibiotics before the surgical in- tervention of first-trimester miscarriage resulted in an insig- nificant decrease in postoperative pelvic infection.

DOI

10.21608/egyfs.2023.286056

Keywords

prophylactic antibiotics, pelvic infection, first-trimester miscarriage

Authors

First Name

Marwa

Last Name

Eid

MiddleName

Mohamed

Affiliation

Assistant Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.

Email

marwameid2014@gmail.com

City

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Orcid

-

First Name

Marwa

Last Name

Magdy

MiddleName

-

Affiliation

Obstetrics and Gynecology resident, Bolak Eldakror hospital, Department of Obstetrics and Gynecology, Bolak Eldakror hospital, MOH, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

El-Sawaf

MiddleName

-

Affiliation

Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

Nihal

Last Name

El-Demiry

MiddleName

M.

Affiliation

Lecturer of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.

Email

-

City

-

Orcid

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Volume

27

Article Issue

1

Related Issue

39711

Issue Date

2023-01-01

Receive Date

2023-02-17

Publish Date

2023-01-01

Page Start

27

Page End

34

Print ISSN

1110-6352

Online ISSN

2536-9768

Link

https://egyfs.journals.ekb.eg/article_286056.html

Detail API

https://egyfs.journals.ekb.eg/service?article_code=286056

Order

286,056

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage

Details

Type

Article

Created At

23 Dec 2024