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Chitosan-Silver Nanoparticles: A Versatile Conjugate for Biotechnological Advancements

Article

Last updated: 23 Dec 2024

Subjects

-

Tags

Section E: Microbiology & Immunology

Abstract

Nano technology has emerged as a powerful field that enables the manipulation and control of matter at the nanoscale. One particular area of interest is the synthesis and application of silver nanoparticles (AgNPs) conjugated with chitosan, a biocompatible and biodegradable polysaccharide. This conjugate offers unique opportunities for various industries, particularly in biomedicine and environmental remediation. In the biomedical field, chitosan-silver nanoparticle conjugates exhibit significant potential as antimicrobial agents, wound dressings, and drug delivery systems. The combination of chitosan's biocompatibility and silver nanoparticles' antimicrobial activity provides an effective approach to combat infections and promote wound healing. Furthermore, the chitosan matrix can facilitate controlled release of therapeutic agents, enhancing their efficacy and reducing potential side effects. In environmental applications,
chitosan-silver nanoparticle conjugates show promise for water purification, as they can effectively remove pollutants and disinfect water due to the antimicrobial properties of silver nanoparticles. Chitosan's ability to form gels and membranes further facilitates their use in filtration systems for wastewater treatment and environmental remediation. In conclusion, the conjugation of chitosan with silver nanoparticles represents a promising avenue in nano technology. This conjugate offers versatile applications in biomedicine and environmental remediation, leveraging the synergistic properties of both components. Further research and development are required to optimize the synthesis techniques, understand the mechanisms of action, and assess the long-term effects to ensure safe and effective utilization of chitosan-silver nanoparticle conjugates in various industries.

DOI

10.21608/aprh.2023.218891.1222

Keywords

Chitosan, Nanoparticles, Conjugate, biotechnology, Antimicrobial

Authors

First Name

Shaimaa

Last Name

Faisal

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University Egyptian Drug Authority (EDA), Cairo 15301, Egypt

Email

shimaafisal89@yahoo.com

City

Cairo

Orcid

-

First Name

Ahmed

Last Name

Hamed

MiddleName

A

Affiliation

Department of Microbial Chemistry, Genetic Engineering and Biotechnology Research Division, National Research Centre, Giza, Egypt

Email

ahmedshalbio@gmail.com

City

-

Orcid

-

First Name

Riham

Last Name

Shawky

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Ain Helwan 11795, Cairo, Egypt.

Email

dr.rihamshawky@pharm.helwan.edu.eg

City

Cairo

Orcid

-

First Name

Mohamed

Last Name

Emara

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Ain Helwan 11795, Cairo, Egypt.

Email

mohamed_emara@pharm.helwan.edu.eg

City

Cairo

Orcid

0000-0001-7708-9435

Volume

7

Article Issue

3

Related Issue

42663

Issue Date

2023-07-01

Receive Date

2023-06-20

Publish Date

2023-07-01

Page Start

163

Page End

169

Print ISSN

2357-0547

Online ISSN

2357-0539

Link

https://aprh.journals.ekb.eg/article_309528.html

Detail API

https://aprh.journals.ekb.eg/service?article_code=309528

Order

4

Type

Review Article

Type Code

358

Publication Type

Journal

Publication Title

Journal of Advanced Pharmacy Research

Publication Link

https://aprh.journals.ekb.eg/

MainTitle

Chitosan-Silver Nanoparticles: A Versatile Conjugate for Biotechnological Advancements

Details

Type

Article

Created At

23 Dec 2024