Aim: This study aimed to evaluate the internal fit and marginal adaptation of 3D printed vs CAD/CAM milled provisional anterior crowns. Materials and methods: Sixteen 3D printed resin models were fabricated and classified into two groups according to the provisional crown construction technique; group 1: received CAD/CAM milled PMMA crowns (n=8), and group 2: received 3D printed PMMA crowns (n=8). The silicone replica technique was used to evaluate the internal fit, while the vertical marginal gap distance was evaluated using a stereomicroscope. Statistical analysis was performed with SPSS 16 ® (Statistical Package for Scientific Studies). The data for all groups was reported as mean and standard deviation. The provided data was analyzed using the Shapiro-Wilk test and the Kolmogorov-Smirnov test to assess normality. Comparison between different surfaces was performed using the One-Way ANOVA test followed by Tukey`s Post Hoc test for multiple comparisons. Comparison between 2 groups was performed by using an independent t-test. Results: there was a statistically significant difference between the two groups. The milled group showed a significantly lower internal gap and vertical marginal gap distance than the 3D Printed group (P=0.0001). Conclusion: The CAD/CAM milled PMMA provisional crowns showed better internal fit and marginal adaptation than the 3D Printed PMMA provisional crowns. Both techniques reported clinically acceptable results.