Aim: The present study was performed to evaluate the effect of injecting minimally cross linked hyaluronic acid using a softfil cannula® & polydioxanone (PDO) smooth threads on restoring the lip texture, elasticity and firmness through collagen induction.

Methods: Fifty female patients were included in the study who suffered from dry lips with fissures and cracks. All patients were injected with Restylane Vital ® (a minimally cross linked hyaluronic acid) using a softfil cannula® followed by placement of PDO smooth threads (I – Thread®) at the vermillion border. Digital pictures were taken before the injection and immediately after the injection for assessment of the clinical results as well as during the follow up periods. All patients were re-injected with Restylane Vital at 3 month & 6 months.

Results: Marked improvement in the lip texture and elasticity were observed at 2 weeks after the injection which remained stable up to nine months after treatment. Moreover there was a marked decrease in the depth of the fissures and cracks in the lips.

Conclusion: Non or minimally cross linked hyaluronic acid injection into the lips along with smooth threads may offer a great improvement for dry lips with loose tissue and decreased elasticity. This can be further improved by repeated skin booster injections along two different intervals from the baseline treatment.