Introduction:Hypomineralized ,discolored enamel is a common defect affecting permanent teeth of children and young adults, microabrasion is one of the commonly used conservative treatments to such a defect .Objective: To compare the efficacy of enamel microabrasion using Opalsture(6.6%HCL) and Antivet(21%HF).Materials and methods: 24 participants free from any systemic disease aged from 9years to 18years old were included in the study those participants were suffering from stained hypomineralized teeth having the following inclusion criteria: Teeth with Degree 1(mild) hypomineralization according to the Wetzel and Reckel scale, were consent for treatment and caries-free teeth.Before treatment base line data were recorded regarding teeth sensitivity through 10points verbal rating scale and visual analog scale(VAS) and documentation was made by photographs. Participants were randomly allocated either to the Opalustre group where patients in this group were treated using (Opalustre, Ultradent Products, USA), or the Antivet group where patients in this group were treated using (Antivet- Dental Continental, México). Teeth sensitivity then was assessed immediately after procedure, 1month and 3months and documentation was made by photographs, the patient satisfaction was assessed by 7points lickert scale. Results: Teeth sensitivity was significantly the highest post-operative immediately as it was(1.67 ± 1.72)and(0.42 ± 0.67) regarding Opalustre and Antivet respectively. Opalustre group (1.67 ± 1.72)was significantly higher than Antivet(0.42 ± 0.67)immediately postoperative. Comparing patient satisfaction in both groups, Opalustre group(2.42 ± 0.67)was significantly lower using Lickert scale than the Antivet group.Conclusion: According to the results of current study, Antivet is a promising product in management of discolored enamel.