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Bone gain in alveolar cleft repair combining Hyaluronic acid with anterior iliac crest corticocancellous graft

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Oral and Maxillofacial Radiology
Oral and Maxillofacial Surgery

Abstract

Purpose: This study aims to evaluate the osteogenic effect of adding Hyaluronic acid (HLA) gel to anterior iliac crest corticocancellous graft for secondary alveolar cleft repair. Methods: The study included forty patients with unilateral alveolar cleft scheduled for repair using autogenous bone graft from the iliac crest. The included patients were divided into two groups. HLA group underwent alveolar bone grafting mixed with Hyaluronic acid gel while the control group underwent alveolar bone grafting alone from the iliac crest. CBCT images were obtained at 1 week and at 6 months following the procedure. The gained bone volume and density were assessed and compared between the two groups. Results: At the end of the follow up period, the HLA group showed more bone gain with higher density compared to the control group. Conclusion: The addition of Hyaluronic acid to bone graft showed uneventful healing and showed an osteogenic potential with increased amount of bone gain.

DOI

10.21608/edj.2023.221678.2628

Keywords

Alveolar cleft grafting, HLA, CBCT, Hyaluronic acid

Authors

First Name

Mahmoud

Last Name

Hanafy

MiddleName

-

Affiliation

Lecturer of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo. Lecturer of Oral & Maxillofacial Surgery, School of Dentistry, New Giza University, Giza,

Email

mahmoud.hanafy@dentistry.cu.edu.eg

City

-

Orcid

0000-0002-1830-5801

First Name

Mina

Last Name

Zaki

MiddleName

-

Affiliation

BDS, MSc, Researcher of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo

Email

mina.nazih@dentistry.cu.edu.eg

City

-

Orcid

0009000596388023

First Name

Tarek

Last Name

El Faramawi

MiddleName

-

Affiliation

Lecturer of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo

Email

tarek.faramawi@dentistry.cu.edu.eg

City

-

Orcid

0000-0001-7838-9560

First Name

alaa

Last Name

nawwar

MiddleName

-

Affiliation

Associate professor, Oral and Maxillofacial Radiology Department, Faculty of Dentistry, Cairo University. Giza, Egypt, Associate professor of Oral and Maxillofacial Radiology, School of Dentistry, New Giza University, Giza

Email

alaa.nawwar@ngu.edu.eg

City

-

Orcid

000000015481135

First Name

Waleed

Last Name

Esmael

MiddleName

Fathy

Affiliation

Lecturer of Oral and Maxillofacial Surgery, Future University in Egypt

Email

waleed.fathy@fue.edu.eg

City

-

Orcid

0000-0001-8400-1649

First Name

Mohammed

Last Name

Khashaba

MiddleName

-

Affiliation

Associate professor of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo

Email

mohammedkhashaba@dentistry.cu.edu.eg

City

Giza

Orcid

0000000156322357

Volume

69

Article Issue

4

Related Issue

43595

Issue Date

2023-10-01

Receive Date

2023-07-12

Publish Date

2023-10-01

Page Start

2,619

Page End

2,625

Print ISSN

0070-9484

Online ISSN

2090-2360

Link

https://edj.journals.ekb.eg/article_318222.html

Detail API

https://edj.journals.ekb.eg/service?article_code=318222

Order

318,222

Type

Original Article

Type Code

254

Publication Type

Journal

Publication Title

Egyptian Dental Journal

Publication Link

https://edj.journals.ekb.eg/

MainTitle

Bone gain in alveolar cleft repair combining Hyaluronic acid with anterior iliac crest corticocancellous graft

Details

Type

Article

Created At

23 Dec 2024