Introduction: Dental caries in its initial phase formation can be remineralized by using fluoride, Although fluoride could be considered the first choice in caries prevention, overexposure to fluoride especially in children can cause side effects, so we need alternatives materials such as Theobromine and silver diamine fluoride that the most promising materials in the remineralization of demineralized enamel due to their advantages.
Purpose: To compare between the solution forms of both theobromine and silver diamine fluoride in the remineralization potential of the demineralized human enamel.
Materials & Methods: twenty sounds mandibular first premolar were divided into 4 equal groups (5 samples each):Control group (C) , demineralization group (D) subjected to demineralizing solution then 5 days PH cycle. The
remaining two groups were similar to demineralization group with addition of treatment material “theobromine solution (T) and silver diamine fluoride solution (S) ,The samples were investigated by scanning electron microscope (SEM) and energy dispersive x-ray analysis (EDXA).
Results: The enamel of demineralization group was porous exposing the subsurface enamel rods with severe rod core defects. Theobromine solution group showed improvement of the enamel surface, silver diamine Fluoride solution also showed improvement in the enamel surface but less than theobromine. EDXA revealed that the calcium phosphorus ratio displayed a descending order: (C > T > S > D).
Conclusion: Theobromine solution and silver diamine fluoride are more effective remineralizing agents. But silver diamine Fluoride solution less than theobromine