Numerous countries, including Egypt, are confronted with higher education challenges, particularly during times of crisis. The adoption of e-learning has been globally recognized as an effective solution to overcome these challenges. The e-learning module was developed based on the anatomy of the lungs in native breeds of domestic animals, such as donkeys, buffaloes, goats, camels, and dogs, using various techniques such as gross anatomy, radiography, and preparation of museum specimens .The study revealed that there was a correlation between the pattern of lobar bronchi and the lobation of the lungs of various animal species. Generally, the right lung of animals usually has four lobes (cranial, middle, caudal, and accessory), while the left lung commonly has a cranial and caudal lobe. Moreover, the number of lobes in some animals may vary. The development of the e-learning module involved electronic tools, a Learning Management System (LMS), a hosting platform (http://vetmed-academy.com), different learning strategies, and a post-course evaluation survey. Upon implementing the e-learning module, a survey of 45 undergraduate students showed positive feedback regarding course expectations, structure, content, quizzing, timing, e-learning pace, navigation, multimedia, and interactivity. Nonetheless, the responses regarding Information and Communication Technology (ICT) and internet services issues were less favorable. According to the study, digital technologies play a crucial role in facilitating effective e-learning by providing infrastructure, devices, resources, content, and related services. Additionally, Information and Communication Technology (ICT) has become an indispensable tool for delivering curricula to learners across the globe.