This study investigated the effect of utilizing antibiotic (Tylosin) and yeast (Saccharomyces cerevisiae), as growth promoters, on the quail chicks' growth performance from day one to forty-two. During the first week of the trial, a basal diet consisting of 24% protein and 2800 Kcal ME/kg was given to each chick. From day seven of age, chicks were randomly divided into seven treatments (30) quail chicks each / three replicates. The dietary treatments were T1; control, chicks received basal diet, and T2, T3, and T4; chicks received basal diet + 1, 2 and 3 g yeast /kg diet, respectively. Whereas, T5, T6 and T7; chicks received basal diet + 0.1, 0.2, and 0.3 g Tylosin‎ /kg diet, respectively. The findings demonstrated that chicks fed on a diet with 3 g yeast /kg diet had the heaviest final body weight and the best FCR (P≤0.05). In contrast to the other treatments, chicks received a diet with 2 g yeast /kg diet had the lowest feed intake. While, those fed on the diet with 0.1 g Tylosin /kg diet had higher feed intake (P≤0.05). When compared to the control group, the birds fed a diet containing 2 and 3 g/kg of yeast had the highest values of net revenue and economic efficiency. When comparing the various therapies to the control group, there was a statistically significant effect on blood biochemical markers. Conclusively, the results conclude that when yeast (Saccharomyces cerevisiae) was added to broiler quail's diet, both performance and economic efficiency increased without any adverse effects.