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354232

Efficacy of Rosmarinus officinalis L. and FeCl3 Extracts on Some Biochemical Parameters during Treatment of Epilepsy in Male Rats Models

Article

Last updated: 23 Dec 2024

Subjects

-

Tags

Veterinary Pathology & Animal Diseases

Abstract

The research methodology included evaluating changes in antioxidants and fat oxide levels. Sixty (60) male mice were divided into six groups: control (no additional treatment), FECL3 group, and four groups managed with different components of Rosmarinus Officinalis L. (flavonoid, glycoside, and alkaloids). Show the results,  elevated levels of β-secretase, Na, and K in the FeCl3 group and the groups receiving Rosmarinus officinalis L. components. Conversely, compared to the FeCl3 group, those administered with Rosmarinus officinalis L. components exhibit levels of Fucose, Invins-C, and Zn. In terms of oxidant enzyme activity and the lithe oxidation, the FeCl3 group showed significant increases in GSH, MDA, SOD, and CAT compared to the control group. However, the Rosmarinus officinalis L. components resulted in elevated levels of MDA and SOD, along with reduced GSH and CAT levels. In conclusion, the components extracted from Rosmarinus officinalis L. β-securecuresed effects on β-Secretase, Fucose, and Voxidantts, in addition to modulating antioxidant activity and lipid peroxidation constituent's sartivevcenreduces the costolesfficinalis L. active constituents The aim of the a novel class of anti-epileptic medications. 

DOI

10.21608/ejvs.2024.277075.1920

Keywords

Rosmarinus officialis, β-Secretase, GSH, FeCl3

Authors

First Name

ali

Last Name

saadi

MiddleName

mohammed

Affiliation

Northern Technical University

Email

ali.mohammed@ntu.edu.iq

City

-

Orcid

0000-0002-5779-1937

Volume

56

Article Issue

3

Related Issue

47550

Issue Date

2025-03-01

Receive Date

2024-03-15

Publish Date

2024-03-01

Page Start

493

Page End

499

Print ISSN

1110-0222

Online ISSN

2357-089X

Link

https://ejvs.journals.ekb.eg/article_354232.html

Detail API

https://ejvs.journals.ekb.eg/service?article_code=354232

Order

354,232

Type

Original Article

Type Code

140

Publication Type

Journal

Publication Title

Egyptian Journal of Veterinary Sciences

Publication Link

https://ejvs.journals.ekb.eg/

MainTitle

Efficacy of Rosmarinus officinalis L. and FeCl3 Extracts on Some Biochemical Parameters during Treatment of Epilepsy in Male Rats Models

Details

Type

Article

Created At

23 Dec 2024