This study aims to determine the effect of effective microorganism utilizing on growth performance, haematological parameters and heat shock protein in quails exposed to heat stress. A one days aged birds were used  for 45 days of the experiment. The experiment were executed by comparing the control group with other three groups (heat group for 8hr thermal  at 37-38 Celsius daily from 07 am:00-1pm,Effective Microorganism group treated with  drinking water 1000ppm dose  and the fourth groups treated with effective microorganism and exposed to heat stress  ) .quails weight measurements were carried out during 7,14,21,28 and 35 days  in addition to body weight gain  ,haemoglobin ,packed cell volume  and heat shock proteins  .The collected data was analysed by one and two way ANOVA test utilizing statistical social science (SPSS).The finding show that effective microorganism had highly significant effects at p ≤0.05 on growth performance  and blood parameters ,while heat shock proteins  level showed no significant interaction expect the heat group and during the last week of the experiment. The result refer that Effective microorganism might be a main effective factor for chicken production to reduce thermal stress,eventually protects the chicken industry ,particularly in hot spot environment areas.