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341255

Incidence of aac(6′)-Ib-cr Mediated by Class 1 Integrons in Aeromonas Species Isolated from Diseased Oreochromis niloticus

Article

Last updated: 01 Jan 2025

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Tags

Veterinary Pathology & Animal Diseases

Abstract

The virulent clonal populations of Aeromonas spp. are recognized as the etiological agent of motile Aeromonas septicemia (MAS) outbreaks in aquaculture. This study aimed to identify Aeromonas spp. isolated from diseased Oreochromis niloticus, evaluate their virulence factors, and assess their resistance to antimicrobial agents. Species identification was conducted through analysis of the gyrB genes. Antibiotic resistance phenotypes and genotypes (blaTEM, blaCTX-M, aac(6′)-Ib-cr, and  intI1) were determined. The results indicated that 44,4% of the isolates belonged to A. veronii, 38.9% to A. sobria, and 16.7% to A. hydrophila. PCR analysis revealed the presence of blaTEM, aac(6′)-Ib-cr, and intI1 genes among 100%, 77.8%, and 83.3% of the isolates, respectively, while blaCTX-M was not detected. In conclusion, the detection of the aac(6′)-Ib-cr gene in aquatic environments can serve as a significant indicator of multi-drug resistance (MDR). The presence of MDR, particularly mediated by integrons in Aeromonas, raises serious concerns regarding potential health risks. Moreover, the emergence of MDR complicates the efficacy of therapeutic treatments for infections. Therefore, adopting a comprehensive One Health approach becomes imperative to effectively control the spread of MDR and mitigate its impact on public health.

DOI

10.21608/ejvs.2024.253308.1701

Keywords

Aeromonas spp, Oreochromis niloticus, Virulence genes, antimicrobial resistance genes

Authors

First Name

Abdelgayed

Last Name

Younes

MiddleName

M.

Affiliation

Hydrobiology Department, Veterinary Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

tahoon176@yahoo.com

City

Kafr El-Sheikh

Orcid

0000-0003-2033-9653

First Name

Alkhateib

Last Name

Y. Gaafar

MiddleName

-

Affiliation

Hydrobiology Department, Veterinary Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

-

City

-

Orcid

-

First Name

Elham

Last Name

S. Awad1

MiddleName

-

Affiliation

Hydrobiology Department, Veterinary Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

-

City

-

Orcid

-

First Name

Waleed

Last Name

S. Soliman

MiddleName

-

Affiliation

Hydrobiology Department, Veterinary Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

-

City

-

Orcid

-

First Name

Marwa

Last Name

B. Salman

MiddleName

-

Affiliation

Department of zoonotic diseases, Veterinary Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

F. Eida3

MiddleName

-

Affiliation

Microbiology Department, Agriculture Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

-

City

-

Orcid

-

First Name

Laila

Last Name

A. Mohamed

MiddleName

-

Affiliation

Hydrobiology Department, Veterinary Division, National Research Centre, Dokki, Cairo, 12622, Egypt

Email

-

City

-

Orcid

-

Volume

55

Article Issue

6

Related Issue

45998

Issue Date

2024-11-01

Receive Date

2023-12-13

Publish Date

2024-11-01

Page Start

1,553

Page End

1,559

Print ISSN

1110-0222

Online ISSN

2357-089X

Article File

EJVS_Volume 55_Issue 6_Pages 1553-1559.pdf

PDF . 956.9kB

Link

https://ejvs.journals.ekb.eg/article_341255.html

Detail API

https://ejvs.journals.ekb.eg/service?article_code=341255

Order

341,255

Type

Original Article

Type Code

140

Publication Type

Journal

Publication Title

Egyptian Journal of Veterinary Sciences

Publication Link

https://ejvs.journals.ekb.eg/

MainTitle

Incidence of aac(6′)-Ib-cr Mediated by Class 1 Integrons in Aeromonas Species Isolated from Diseased Oreochromis niloticus

Details

Type

Article

Created At

23 Dec 2024