This trial was conducted to explore the effect of nutritional Short-chain fatty acids (SCFAs) such as butyric acid (BA) and medium-chain fatty acids (MCFAs), such as caprylic acid (CA), with or without cinnamon essential oil (CEO). Throughout the late-laying time, on the physiological and productive performance of Sinai hens. The study used 180 females and 18 males varying in age from 60-72 weeks. The results demonstrated that, contrasted with the group under control, including 150 mg cinnamon essential oil (CEO)/ kilogram (T4) or 1g caprylic acid (CA)/ kg (T3) into meals, the feed conversion ratio was significantly (P≤0.05) improved during the study period. By including CA and BA with or without, the optimal value of globulin, albumin/globulin ratio, and total protein in plasma, calcium and estrogen hormone were recorded. cinnamon essential oil to diets of the hens in comparison to the control group. Whereas, After CA and BA addition to the laying hens' diets, there was a drop (P0.05) in the total lipid levels and malondialdehyde (MDA) was seen in their plasma. Both with and without the CEO. The percentages of hatchability and fertility were (P≤0.05) higher in CA and BA with or without cinnamon essential oil (CEO) treated groups as opposed to the control group. Overall Escherichia coli (E. coli) counts was decreased. In conclusion, whether adding cinnamon essential oil or not, the physiological as well as productive performance of the Sinai laying hens was enhanced by feeding them short and medium-chain fatty acids throughout the late laying stage.