The role and action of the active chemical compounds and native flowers to improve immunity system faction and behavior in the broiler. This study has investigated the impact of adding some neurotransmitters (Endorphin, Dopamine, and Serotonin) in drinking water and native Hero flowers (Alcea kurdica) in diets on behavior, immune status, and growth of broilers (Ross-308). 720 unsexed hatched chicks will be distributed into 8 groups; T0 (control -standard diet), [T1 (0.2 gr endorphin), T2 (0.2 gr dopamine) and T3 (0.2 gr serotonin)/ L drinking water], [T4 )0.5 kg Hero flower (Hf))/100 kg diet], T5 )0.2 gr endorphin + 0.5 kg Hf(, T6 (0.2 gr dopamine + 0.5 kg Hf (, T7 )0.2 gr serotonin+ 0.5 kg Hf (. The results of neurotransmitters and Hf additives led to a significant (P≤0.01) increase in eating behavior when birds were in an up position, wing flapping, dust bathing, walking and preening, serum concentrations of endorphin, dopamine, serotonin, immunoglobins IgG, IgA, IgM, and antibodies titer against Newcastle (ND), and Infectious Bronchitis Viral (IBV) diseases compared with control T0, improved histological of Bursa, body weight, body weight gain, improved feed conversion ratio (FCR), and pathohistology bursa of Fabricius , and feasibility. While the results of eating when birds were at set position, immobility, pecking, feather pecking, aggressiveness and mortality percentages were decreased.