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332094

Impact of Spirulina platensis as a Dietary Supplement on Growth Performance, Blood Biochemical Parameters, and Expression of Growth-Related Genes in Nile Tilapia (Oreochromis nil

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Physiology & Animal Nutrition

Abstract

The present investigation was designed to verify the effect of using Spirulina platensis (Sp) on growth performance, blood biochemical parameters, and expressions of growth hormone (GH), growth hormone receptor (GHR), insulin-like growth factor1 (IGF-1), insulin-like growth factor 2 (IGF-2), and myostatin (MSTN) genes in Nile tilapia. A total of 96 fingerlings (12 ± 0.2 g) were randomly allocated into eight groups, each containing 12 fish, and fed diets containing 0%, 1% (10 g), 2% (20 g), and 3% (30 g) SP/kg for 8 weeks. Significant improvements in growth were observed in the 1% SP group, with the best feed conversion rate at 1.09. Biochemical parameters, including serum protein, globulin, liver enzymes (ALT and AST), cholesterol, and glucose concentrations, were analyzed using a spectrophotometer for calorimetric analysis. Higher serum protein and globulin levels were observed in the 1% SP group compared to the control. RT-PCR analysis indicated elevated GH expression in the brain and muscles, along with increased IGF-1 and IGF-2 levels observed in the liver and muscle tissues of the 1% SP group compared to the control and other treatments. However, there was a positive correlation between the 1% SP diet and enhanced MSTN mRNA levels in muscle tissues. Except for higher ether extract (EE) in the 2% SP treatment, there were no significant changes in fish survival or body composition. Overall, this study recommends utilizing 1% SP as a dietary supplement to improve growth, feed utilization, biochemical parameters, and growth-related gene expressions in Nile tilapia.

DOI

10.21608/ejvs.2023.250660.1678

Keywords

Spirulina, Nile tilapia, Growth performance, blood biochemical parameters, growth-related gene expressions

Authors

First Name

Hesham

Last Name

Abozaid

MiddleName

-

Affiliation

Department of Animal Production, Agricultural and Biology Institute. National Research Centre, Dokki, Giza, 12622, Egypt.

Email

genesiarona@gmail.com

City

-

Orcid

0000-0003-4340-1157

First Name

Ali

Last Name

Elnady

MiddleName

-

Affiliation

Affiliation: Department of Cell Biology, Biotechnology Research Institute, National Research Centre, Dokki, Giza, 12622, Egypt.

Email

ali_elnady_nrc@yahoo.com

City

-

Orcid

-

First Name

Dalia

Last Name

Aboelhassan

MiddleName

M

Affiliation

Department of Cell Biology, Biotechnology Institute, National Research Centre, Egypt

Email

dalia_hemdan@yahoo.com

City

-

Orcid

0000-0003-4340-1157

First Name

Hayam

Last Name

Mansour

MiddleName

-

Affiliation

33 ElBohouth

Email

hayammansour@hotmail.com

City

Dokki

Orcid

0000-0003-2934-4125

First Name

Abdelmegid

Last Name

Abedo

MiddleName

-

Affiliation

National Research Center, Egypt , NRC · Department of Animal Production

Email

abedoaa@yahoo.com

City

-

Orcid

-

First Name

Hashim

Last Name

Abdel rahman

MiddleName

-

Affiliation

Department of Animal Reproduction, Agricultural and Biological Research Division, NRC.

Email

hshm_abdelrahman@yahoo.com

City

-

Orcid

-

First Name

Inas

Last Name

Ghaly

MiddleName

S

Affiliation

Affiliation: Department of Cell Biology, Biotechnology Research Institute, National Research Centre, Giza, Egypt.

Email

inassalahghaly@yahoo.com

City

Giza

Orcid

0000-0003-3425-7341

First Name

Hasnaa

Last Name

Radwan

MiddleName

-

Affiliation

National Research Centre

Email

radwan_hasnaa@yahoo.com

City

-

Orcid

0000-0003-2192-7705

First Name

Wafaa

Last Name

Abbas

MiddleName

-

Affiliation

NRC

Email

dalia.aboelhassan@yahoo.com

City

-

Orcid

-

First Name

Ibrahim

Last Name

Farag

MiddleName

M.

Affiliation

Department of Cell Biology, Biotechnology Research Institute, National Research Centre, Giza, Egypt.

Email

faragim@hotmail.com

City

Giza

Orcid

0000-0002-7918-9437

Volume

54

Article Issue

6

Related Issue

42607

Issue Date

2023-11-01

Receive Date

2023-11-23

Publish Date

2023-11-01

Page Start

1,265

Page End

1,277

Print ISSN

1110-0222

Online ISSN

2357-089X

Article File

EJVS_Volume 54_Issue 6_Pages 1265-1277.pdf

PDF . 1.4MB

Link

https://ejvs.journals.ekb.eg/article_332094.html

Detail API

https://ejvs.journals.ekb.eg/service?article_code=332094

Order

332,094

Type

Original Article

Type Code

140

Publication Type

Journal

Publication Title

Egyptian Journal of Veterinary Sciences

Publication Link

https://ejvs.journals.ekb.eg/

MainTitle

Impact of Spirulina platensis as a Dietary Supplement on Growth Performance, Blood Biochemical Parameters, and Expression of Growth-Related Genes in Nile Tilapia (Oreochromis nil

Details

Type

Article

Created At

23 Dec 2024