Abstract:
Clinical anesthetic trial was conducted on 12 local dogs in different age, sex and body weight. The aim of study is to investigate the compatartive effect of ketamine and xylazine combination injected either IM or IV on the anetshetic (induction times, duration of anesthesia and recovery time) and physiological parameters on the dogs. They were divided into two groups (G-I and G-II) randomly. All dogs were administered with atropine sulphate (0.04mg\kg BW, IM) 5 minutes before anesthetic protocol, ketamine+xylazine (10mg\kg+1mg\kg) respectively, was adminstered IM in G-I and IV in G-II. Clinical findings including inductions, duration and recovery period of anestehsia, HR, RR, RT, SPO2, SBP, DBP and MAP were recorded before and during anesthesia. The study show that there were no significant differences between G-I and G-II in physiological parameters of ketamine and xylazine anethesia in dogs except induction, duration and recovery of anesthesia was longer in G- I than G-II. In conclusion, the results demonstrated that the combination of ketamine+xylazine can be a special satisfatcory anesthetic protocol for excellent induction, good muscle relaxant and smooth recovery in dogs.