Evaluation of tomato promising hybrids under greenhouse conditions comes in the first order for Plant Breeding and Conservation Program of Desert Research Center (DRC). Evaluation was carried out for eighteen hybrids of tomato at North Sinai and Ismailia locations during 2021/2022 season. Using Line × Tester analysis is a good tool for preliminary evaluation of the breeding program. The experimental design was randomized complete block design with three replicates. The results indicated that tomato hybrids mean squares in the combined data were highly significant for all traits. The interaction between locations and tomato hybrids mean squares were highly significant for all the studied traits, except plant height and number of locules per fruit. Based on the results obtained in the two locations, the most productive and adapted tomato hybrids were identified to greenhouse conditions. S812× STel (12) and S922× SR74 (13) hybrids were performed well at both locations. Yield per plant had positive correlation with all characters, except fruit firmness and TSS percentage that had a negative correlation with yield.