During this study, which spanned from January 2018 to December 2020, fish diseases were investigated, resulting in the recording of 68 disease cases. Of these, 35 were attributed to bacterial gill disease, 15 to skin ulcer disease, 12 to intestinal inflammatory disease, four to high ammonia disease, and two cases of fin rot. Health problems were documented in 39 fish farms over the three-year period, with cases involving 26 ponds covering a total area of 75.05 dunams (1 dunam = 0.25 ha), three fish farms with 10 cages totaling 468m³, and 10 farms employing semi-closed systems with a total area of 1,437.8m³. The highest prevalence of disease (29 cases, or 42.64%) was recorded in 2018. The disease cases were described, and the results were chronologically organized by type of infection, method of fish farming, and the distribution of disease cases across the districts of Basra Governorate.