The Yellowfin fish bone meal contains minerals, especially calcium and phosphorus, which are present in high levels after processing if processed; the benefits are enormous for the human body's needs. This study aimeds to determine the recovery of ovariectomized rat vertebrae using yellowfin bone meal and CaCO₃ therapy. This study consisted of three stages:, namely, firstly, processing yellowfin fish bone waste into fish bone meal with deproteination, non-deproteinization, and calcium carbonate treatment as a comparison. The second stage carried outinvoloved a physicochemical analysis of yellowfin fish bone meal. In tThe third stage used X-rays were used to confirm the extent of spinal damage in ovariectomized rats treated with deproteinized, non-deproteinized fish bone meal and calcium carbonate. The results showed revealed  a significant development of bone remodelling in osteoporosis, that as observed through vertebral observation for four months showed a significant development of bone remodelling in osteoporosis. The bBone is a dynamic tissue that is constantly undergoing remodelling due to mechanical responses and hormonal changes. Bone remodelling occurs in the bone remodelling unit, where there is  an emotional balance between osteoclast bone resorption and bone formation by osteoblasts. In comparison, the observation of via dual-energy absorptiometry x-ray on day 30 with following deproteination therapy at a dose of 1600 mg/ kg B.W. / day showed revealed a very significant change in recovery in vertebral bone radiology.