Edku Wetland is considered one of the most important lakes in northern Egypt. Sixteen polycyclic aromatic hydrocarbons (PAHs) in eight water samples were studied during the spring and summer of 2022 to determine the spatial and seasonal distribution, source of PAHs, toxicity, and ecological risk for the lake water. PAHs were analyzed using gas chromatography. The concentration of ∑16PAHs recorded the lowest values ​​of 115.80 and 54.80ng/ L, which represents the sea-lake contact point during spring and summer, and the highest values ​​of 210.60 and 182.10ng/ L during the same seasons, respectively, which represents the main connection point of the drainage lake. The PAH composition pattern by ring type showed a considerable predominance of the three-ring, four-ring, and six-ring PAHs. To evaluate the possible sources of PAHs, the molecular indices were determined by the calculation of ΣLMW/ ΣHMW, Benzo(a)anthracene/ Chrysene BaA/ (BaA/ Chry), Indeno (1,2, cd) pyrene/ Benzo(g) (In/ BgP), Phenan-threne/Anthracene (Phe/ Ant), and Fluoranthene/Pyrene (Flua/ Pyr) ratios. The results indicate that the significant source of PAHs in the water lake was a pyrogenic source, resulting from the combustion of fuel, wood, and grasses. The toxicity and ecological risk assessment indicates that there were no observed hazard to the environment. Risk quotients suggested the safety of the lake water from the possibility of cancer for BaP toxic equivalents, and incremental lifetime cancer risk being very low.