Bisphenol A (BPA) has attracted worldwide attention as a toxic and endocrine-disrupting substance. It can be released into aquatic habitats through microplastic pollution, harming all aquatic life. To reduce its effects and toxicity, it has been necessary to use biological methods that occur naturally in water and are cheap and easy to obtain, such as algae. For this reason, the cyanobacterium Gloeocapsopsis crepidium was used to test its ability to biodegrade this toxic compound by exposing it to different concentrations of BPA (1, 5, 10, 20, 50, 75, 100) mg/l under controlled laboratory conditions at 25°C and a light intensity of 60 µmol m^-2s^-1. The results of the bioremoval of bisphenol A by the cyanobacterium Gloeocapsopsis crepidium exposed to the different concentrations of BPA (1, 5, 10, 20, 50, 75, 100) mg/l show higher removal efficiencies, the results showed that the highest removal efficiency reached 100% at 1mg/l BPA with residual value 0 mg/l. In contrast, the highest residual value reached 20.52 mg/l at 100 mg/l BPA with a removal percentage of 79.48%. These results are supported by statistical analysis with significant differences at p≤0.05.