The present work aimed to evaluate water pollution with three heavy metals (Cu, Pb and Zn) in Mansoura, El-Mahalla El-Kubra, Tanta, Assiut, Wasta Beni Suef and Shibin Al Qanatir localities, using two freshwater snails: Biomphalaria alexandrina (the intermediate host and vector of schistosomiasis) and Lanistes carinatus as bioindicators. Results showed that the highest concentrations of the three heavy metals were 2.084ppb for Cu found in Tanta, 58.200ppb for Zn in Wasta Beni-Suef, and 20.000ppb for Pb discovered in Assiut. The accumulation of three heavy metals in Lanistes carinatus snail was higher than that in Biomphalaria alexandrina snail. The highest accumulated content inside Lanistes snails was for Cu-metal (36838 ppb) from Wasta Beni-Suef area. It could be concluded that B. alexandrina and L. carinatus are suitable bioindicators for the accumulation of heavy metals pollution.