The application of Moringa oleifera seeds (MOS) powder after extraction as a natural coagulant increases the removal effectiveness of all types of algae. Developing countries have recently given a lot of thought for adopting suitable, affordable technology for drinking purified water. The presence of several species of algae, particularly hazardous forms in the Nile River's waters has attested a review of conventional treatment methods. MOS was the most efficient coagulant, eliminating every algal group from untreated Nile water. The algal removal rate varied between 75% and 96% in the sedimentation basin and between 92% and 97% in the discharge water at doses between 1 and 10 mg/l. The elimination percentage of turbidity was 81.43%, and the turbidity decreased from 8.24 to 1.53 (NTU). Comparative morphology of identifying keys has been used to classify and identify algae, and the Sedgwick-Rafter counting chamber has been used to measure algal abundance. The amount of algae that MOS successfully eliminated from untreated Nile waters and kept in top condition was considerable. In both small- and large-scale water treatment processes, MOS contains a coagulant protein that can take the place of common coagulants such as aluminum salts. By isolating active proteins as coagulants from MOS, it has been proposed to apply them in water treatment.