This study was designed to study the effect of organic pollution on Autotomy in one species of freshwater organism Namalycastis indica  (Southern, 1921)  which was collected during the study period (January  2022 to November  2022) from three sites in Shatt AL-Arab River.  The organisms were exposed to different types of organic pollution in Shatt al-Arab River resulting from sewage, agricultural work, boat movement, and transport carrying oil derivatives and goods. The autotomy was after the tenth ring below the head. This study indicates that the cutting organisms have different signs as response to the parameters of the water quality affected by the oscillation. Also, growth was affected due to the increase in organic pollutants in the water, which leads to a long period of growth in the regenerated parts.