During the year 2021, 870 Actinopterygii fish belonging to four different species were gathered along the Alexandria coast and examined for parasitic copepods. Four different species of parasitic copepods were reported during the period study including Lernanthropus kroyeri Beneden, 1851 from Dicentrarchus labrax (Linnaeus, 1758); Caligus affinis Heller, 1866 reported from Pomatomus saltatrix (Linnaeus, 1766); Mitrapus oblongus Pillai, 1964 from Sardina pilchardus (Walbaum, 1792); and Naobranchia cygniformis Hesse, 1863 were discovered from Boops boops (Linnaeus, 1758). Two of these four species (C. affinis and N. cygniformis) were reported from the Alexandria coast for the first time. Additionally, we recorded a few new host records, one of which included the discovery of M. oblongus on S. pilchardus. Parasitological indices known as prevalence, host-specificity of collected parasites, and their main micro-niches on investigated host species are done, as well as histopathological alternation, was discussed. The inclusion of new records of some parasitic species (C. affinis and N. cygniformis) in the Egyptian ecosystem contributes to enhancing their geographical distribution.