This study provides comprehensive results on the relationship between sea surface temperature (SST) and the atmospheric parameters affecting the southern Levantine Basin, over the period 2007-2018. Such investigation is essential to understand the variations in both the ocean and the atmosphere. Over the study period, the SST showed an increasing trend with a rate of +0.3°C/yr. The mean annual SST was weakly correlated with the mean annual surface air temperature with a correlation coefficient of only +0.15, while the seasonal correlation coefficient between the two parameters was as strong as +0.91. There was a significant negative seasonal correlation (-0.71) between SST and air pressure. The inverse relationship between the SST and surface wind speed was revealed, with a correlation coefficient of -0.54. Meanwhile, there was a substantial seasonal correlation of +0.25 between the SST and wind directions. This study produced empirical relationships that can be applied within the southern Levantine Basin; to calculate SST from the surface atmospheric parameters on a seasonal basis. Results revealed that seasonal correlations between the SST and atmospheric conditions in the southern Levantine Basin are more reliable to investigate the SST changeability tied to these conditions than the annual ones.