Adopting modern techniques in caltivating strategic crops is important, especially in limited land and water resources for horizontal expansion. Technology raises the efficiency of  available resources and wheat crop was chosen for its great importance in increasing Egyptian food security. The research aimed to study the impact of modern technologies on  economic efficiency of wheat crop in the New Valley Governorate, To achieve this goal, a cluster sample was drawn from  Al-Kharga district, divided into two groups according to the cultivated wheat varieties, each group was divided into sub-groups representing farmers who used mechanization. Using the analysis of variance method to compare the different technological groups in terms of economic efficiency. Results show that the third technological combination, which represents farmers high productive seeds with the use of agricultural mechanization, was superior to its counterpart from other combinations. Therefore, the study recommended encouraging farmers to adopt the idea of using the agricultural machine in addition to the high productive seeds in producting wheat crop to included in all cultivated areas in New Valley Governorate.