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Date (Phoenix dactylifera var. Khalas) Seed Extracts Rich in Bioactive Compounds and Antioxidant Activities: Potential Preventive Effects Against Atherosclerosis and Lipid Oxidat

Article

Last updated: 01 Jan 2025

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Subjects

-

Tags

Food Science and technology

Abstract

Date seed extracts (DSE) derived from ethanol, methanol, and water were analyzed for their content of bioactive compounds, antioxidant properties, and their potential roles in preventing atherosclerosis and lipid oxidation in model systems. The ethanolic extract (EtE) was found to contain the highest concentrations of bioactive compounds, including total phenolics, total flavonoids, lycopene, terpenoids, tannins, kaempferol, and phytates. In contrast, the methanolic extract (MeE) contained total carotenoids and polysaccharides, while the aquatic extract (AqE) was noted for compounds such as lutein, total anthocyanins, triterpenoids, saponin, oxalate, and caffeine. Additionally, all DSE exhibited significant antioxidant and radical-scavenging activities. In the DPPT assay, the IC50 values for AqE, EtE, and MeE were determined to be 17.63 ± 0.24, 12.10 ± 0.20, and 14.09 ± 0.13 μg/mL, respectively, in comparison to the BHT standard, which was 9.25 ± 0.19 μg/mL. Consequently, the free radical scavenging activity (FRSA) of the DSE and the standard was ranked as follows: standard (BHT) > EtE > MeE > AqE. Both 50 and 100 ppm concentrations of all DSE demonstrated the capability to inhibit lipid oxidation in both β-carotene linoleate and low-density lipoprotein (LDL) oxidation model systems (Anti-atherosclerotic effect). Therefore, it can be inferred that DSE may serve as a viable alternative source of natural antioxidants. Furthermore, DSE may serve as a potential drug in the prevention

DOI

10.21608/asejaiqjsae.2024.381412

Keywords

Chemical composition, extractive value, antioxidant, DPPH, scavenging, Anti-atherosclerotic effect

Authors

First Name

Doaa

Last Name

Gouda

MiddleName

Omar

Affiliation

Nutrition and Food Sciences- Faculty of Specific education - Sohag university

Email

doaa.gouda8521@gmail.com

City

Sohag

Orcid

6240-9140-0003-0009

First Name

Yousif Abd Elasis Elhassaneen

Last Name

Elhassaneen

MiddleName

-

Affiliation

Department of Nutrition and Food Science, Faculty of Home Economics, Minoufiya University, Shebin El-Kom, Egypt

Email

yousif12@hotmail.com

City

Shebin El-Kom,

Orcid

0000-0003-1391-3653

First Name

Hisham

Last Name

Saad

MiddleName

Hamdy

Affiliation

Faculty of Home Economics, Menoufia University

Email

his_hamdy@yahoo.com

City

Shebin Elkom

Orcid

0009-0003-0906-9872

Volume

45

Article Issue

3

Related Issue

49063

Issue Date

2024-09-01

Receive Date

2024-08-20

Publish Date

2024-09-30

Page Start

535

Page End

550

Print ISSN

1110-0176

Online ISSN

2536-9784

Article File

ASEJAIQJSAE_Volume 45_Issue 3_Pages 535-550.pdf

PDF . 733.0kB

Link

https://asejaiqjsae.journals.ekb.eg/article_381412.html

Detail API

https://asejaiqjsae.journals.ekb.eg/service?article_code=381412

Order

15

Type

Original Article

Type Code

53

Publication Type

Journal

Publication Title

Alexandria Science Exchange Journal

Publication Link

https://asejaiqjsae.journals.ekb.eg/

MainTitle

Date (Phoenix dactylifera var. Khalas) Seed Extracts Rich in Bioactive Compounds and Antioxidant Activities: Potential Preventive Effects Against Atherosclerosis and Lipid Oxidat

Details

Type

Article

Created At

23 Dec 2024