Beta
ManageSearchChatDiscover
315705

Potential Effects of Horny Goat Weed (Epimedium grandiflorum) on The Level of Fertility in Male Rats Infected with Cadmium Chloride: Biochemical and Histopathological Study

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Food Science and technology

Abstract

The present study aimed to investigate the effect of horny goat weed on the level of fertility in male rats infected with cadmium chloride. The rats were divided into two groups, the first group: Group 1 (6 rats) fed on a basal diet as a negative control group (-ve) and the other main groups (30 rats) were injected with two doses of cadmium chloride (CdCl2, 0.1%) administered intraperitoneally at 0.1 ml per 100g body weight to cause sterility and classified into five subgroups. Subgroup 1(n:6): fed on the basal diet as a positive control group (+ve). Subgroup 2 feds on basal diet and given standard drug (Sildenafil Citrate) (SC) (5 mg/kg b w) via a stomach tube daily for 28 days. Subgroup 3,4 and 5 fed on the Horny Goat Weed (HGW) by 10, 15and 20 % (w/w) of the basal diet weight, respectively. Blood samples were taken after the experiment to assess lipid profiles, liver functions, kidney functions, and serum levels of testosterone (T), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). The testicles were removed for histopathological examination, measuring the testicular tissue hormones and antioxidant enzymes superoxide dismutase, glutathione peroxidase, catalase and malondialdehyde. Results indicated that the HGW treatments improved liver, renal function, lipid profiles, antioxidant enzyme activity and sex hormone levels in both serum and testicular tissue.
In conclusion; The moderate use of horny goat weed may be beneficial for improving male sexual performance and is considered as one of the natural sexual stimulants.
 

DOI

10.21608/asejaiqjsae.2023.315705

Keywords

fertility, Horny goat weed, luteinizing hormone, Cadmium chloride, Liver functions

Authors

First Name

Amal

Last Name

Nasef

MiddleName

Z.

Affiliation

Dep. of Nutrition & Food Science, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt

Email

amal.nasif1@hec.menofia.edu.eg

City

-

Orcid

0000-0002-7054-8659

First Name

Naglaa A.

Last Name

El-Sheikh

MiddleName

-

Affiliation

Dep. of Nutrition & Food Science, Faculty of Home Economics, Menoufia University, Shibin El-Kom, Egypt

Email

naglaa.ali45@yahoo.com

City

-

Orcid

-

Volume

44

Article Issue

3

Related Issue

42489

Issue Date

2023-09-01

Receive Date

2023-08-10

Publish Date

2023-09-30

Page Start

433

Page End

443

Print ISSN

1110-0176

Online ISSN

2536-9784

Article File

ASEJAIQJSAE_Volume 44_Issue 3_Pages 433-443.pdf

PDF . 1.2MB

Link

https://asejaiqjsae.journals.ekb.eg/article_315705.html

Detail API

https://asejaiqjsae.journals.ekb.eg/service?article_code=315705

Order

14

Type

Original Article

Type Code

53

Publication Type

Journal

Publication Title

Alexandria Science Exchange Journal

Publication Link

https://asejaiqjsae.journals.ekb.eg/

MainTitle

Potential Effects of Horny Goat Weed (Epimedium grandiflorum) on The Level of Fertility in Male Rats Infected with Cadmium Chloride: Biochemical and Histopathological Study

Details

Type

Article

Created At

23 Dec 2024